Surname De Gregorio (De Gregorio 
) , worldwide, is quite a common family name. The cognomen De Gregorio is habitual in Italy, where it is quite a common surname, Argentina, where it is quite a rare surname, and Uruguay, where it is a rare surname. Not in comparison with a country's population, it is the most numerous in Italy, Argentina, and Mexico.
| VARIANT | COUNTRY |
|---|---|
| De Gregorio | Spain, Italy, Mexico, France, Argentina |
Degregorio, Di Gregorio, and Digregorio
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pietro de gregorio Ilian jurist from Messina (16th century), IT (b. 1480) |
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leopoldo de gregorio Italian statesman (1699-1785), IT (b. 1699) |
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emmanuele de gregorio Catholic cardinal, ES (b. 1758) |
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| giovanni de gregorio Italian cardinal (1729-1791), IT (b. 1729) |
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| anna de gregorio Spanish noblewoman (1802-1886), ES (b. 1802) |
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| rocco de gregorio Roman Catholic bishop (1803-1858) (b. 1803) |
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| marco de gregorio Italian painter (1829-1876), IT (b. 1829) |
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| antonio de gregorio Italian malacologist (1855-1930) (b. 1855) |
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| giacomo de gregorio Italian historical linguist, IT (b. 1856) |
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| salvatore de gregorio Italian painter (1859-1928), IT (b. 1859) |
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| giuseppe de gregorio Italian musician and lyricist, IT (b. 1866) |
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| antonio de gregorio rocasolano Spanish chemist, ES (b. 1873) |
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| eduardo de gregorio garcía-serrano ES (b. 1899) |
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josé de gregorio Chilean economist, academic, and politician, CL (b. 1959) |
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sergio de gregorio Italian journalist and politician, IT (b. 1960) |
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